- Fadairo, J.K, Daniels*1, A.O.2 Baale, P.M3, Abegunde, J.O.4 Izeko, I.L.5
- MSI Journal of Medicine and Medical Research (MSIJMMR)
Abstract: Excessive bleeding following surgery can be a significant complication, often linked to deficiencies in clotting factors. Perioperative hemostasis monitoring is crucial to enhance patient safety during surgical procedures.
This study aimed to assess changes in Prothrombin Time (PT), Activated Partial Thromboplastin Time (aPTT), and platelet count in patients before and after surgery at UNIMEDTHC Ondo. A total of 45 patients (42 females and 3 males) admitted to various wards at UNIMEDTHC Ondo consented to participate. Data was collected over a two-month period using questionnaires and blood samples. Blood samples (6 mL) were drawn pre-operatively and 24 hours post-operatively. PT, aPTT, and platelet counts were analyzed manually using Agape reagents. Statistical analysis was performed using SPSS version 25. Results indicated a slight increase in PT and INR post-operatively, a decrease in aPTT, and a significant increase in platelet count. However, no statistically significant differences were observed in PT, aPTT, and platelet count between pre- and post-operative patients. Furthermore, no significant differences were found in these parameters based on age or gender.
Keywords: Pre-operative, Post-operative, Prothrombin time (PT), Activated partial thromboplastin time (aPTT), Platelet count.
